Children’s Cancer Centre Biobank (CCC)
The Children’s Cancer Centre (CCC) Biobank is a world-class resource for researchers studying childhood and adolescent/young adult cancer. The CCC Biobank includes samples and health information from people with cancer, bone marrow disorders, primary immunodeficiency disease and neurofibromatosis. It also includes samples and health information from their siblings, parents and relatives.The CCC Biobank stores leftover samples from clinical tests and takes additional collections.
The CCC Biobank allows researchers to: understand the molecular mechanisms which lead to cancers and other conditions, establish new molecular-based diagnostic tests, investigate biology using cell lines, test new drugs and therapies, identify new targets for therapy, and reduce the debilitating side effects of treatment.
| Study Summary | |
|---|---|
| Study name | Children’s Cancer Centre Biobank |
| Study abbreviation | CCC |
| Current principal investigator/s |
David Eisenstat |
| Current project manager |
Louise Ludlow |
| Primary Institution/s |
Murdoch Children’s Research Institute - MCRI
|
| Collaborating Institution/s |
The Royal Children’s Hospital - RCH
|
| Major funding source/s |
The Royal Children’s Hospital Foundation - RCHF |
| Study website | https://www.mcri.edu.au/research/projects/childrens-cancer-centre-biobank |
| Study focus |
The CCC Biobank stores leftover samples from clinical tests and takes additional collections. These samples can be used for further clinical testing and ethically approved research. |
| Sampling frame |
New or existing patients attending The RCH with a suspected tumour, bone marrow disorder, Primary Immunodeficiency Disease, Neurofibromatosis or giant melanocytic naevi. Or, a sibling, parent or relative of a patient described above. |
| Primary study type | Databank / Biobank |
| Primary participant (at recruitment) | Index child |
| Year commenced |
2014 |
| Is this study ongoing? | Yes - the study is ongoing |
| Ongoing recruitment? | Yes |
| Sample size (N) |
1800 (as of May 2023) |
| Survey data available? | No |
| Imaging data available? | Yes |
| Linkage to administrative dataset/s? | No, no consent to link to administrative dataset(s) obtained |
| Biosamples available? | Yes |
| Are data available to others outside study team, with appropriate safeguards and structures in line with the cohort’s ethics and governance processes? | Yes |
| Are there any costs associated with data/sample access for approved requests? | Yes, there are costs associated with access |
| Broadest type of participant consent available |
Extended consent (can be used for future ethically approved research related to this project) |
| Study Contacts | |
|---|---|
| Principal investigator/s |
David Eisenstat |
| Project manager |
Louise Ludlow |
| Study Contact |
Address: The Children’s Cancer Centre Biobank |