The LSAC Child Health CheckPoint is a new phase of the Growing Up in Australia study. It is a one-off physical health check-in that is being conducted during 2014-15. The aim is to learn more about the health of young Australians as they pass through the ‘checkpoint’ between being children and teenagers. Therefore, it involves the younger LSAC children, born in 2003-4. Because the CheckPoint needs special equipment and skills, its staff are from the Murdoch Childrens Research Institute and are supervised by Growing Up in Australia’s senior health researchers. LSAC’s main waves have happened every 2 years since 2004. After the 6th wave, the study will invite 11 and 12 year olds to take part in health activities which will enable researchers to learn about heart and lung health, fitness, strength, vision, diet, activity, and more.




Year 2004 2006 2008 2010 2012 2014 2015 2016
Wave 1 2 3 4 5 6 CheckPoint 7
Age 3-19 months 2-3 years 4-5 years 6-7 years 8-9 years 10-11 years 11-12 years 12-13 years
# 5107 4606 4386 4241 4070 3764 1875 (plus 1875 parents) To be determined
Identifiers
Allergies
Anthropometrics
Cardiovascular health
Demographics
Education
Environmental exposures (toxins and allergens)
General health
Hearing
Medication
Mental health
Nutrition
Physical activity and lifestyle
Puberty
Resilience and wellbeing
Respiratory health
Linkage to other databases
Biosamples
Year 2004 2006 2008 2010 2012 2014 2016
Wave 1 2 3 4 5 6 7
Age 4-5 years 6-7 years 8-9 years 10-11 years 12-13 years 14-15 years 18-19 years
# 4983 4468 4331 4164 3930 3537 To be determined
Melbourne Children’s Consortium for Lifecourse Research Study Summary
Study name Growing Up in Australia’s Child Health CheckPoint
Study abbreviation LSAC
Current principal investigator/s Professor Melissa Wake
Chief Investigator Group Prof Melissa Wake, Prof John Carlin, Dr Fiona Mensah, Assoc/Prof Lisa Gold, Assoc/Prof Sarath Ranganathan, Prof Tim Olds, Prof Dave Burgner, Assoc/Prof Michael Cheung, Prof Michael Sawyer, Prof Terry Dwyer
Associate Investigator Group Dr Ben Edwards, Dr Helen Rogers, Prof Louise Baur, Prof Steve Zubrick, Prof Tien Wong, Dr Richard Saffery, Dr Peter Azzopardi, Mr Luke Stevens, Dr Matt Sabin, Dr Peter Simm, Dr Jessica Boyce, Ass Prof James Sharman, Prof Jonathon Craig, Dr Siah Kim
Primary Institution Murdoch Childrens Research Institute
Collaborating Institutions
  • The Longitudinal Study of Australian Children – which is conducted in partnership between the Department of Social Services, Australian Institute of Family Studies and the Australian Bureau of Statistics
  • University of South Australia, the University of Adelaide, and Deakin University
Major funding sources NHMRC
Study website www.lsac-childhealthcheckpoint.org.au
Key reference for study (published study protocol) Wake, Melissa; Clifford, Susan; York, Elissa; Mensah, Fiona; Gold, Lisa; Burgner, David and Davies, Sarah. Introducing growing up in Australia’s child health check point: A physical health and biomarkers module for the longitudinal study of Australian children [online]. Family Matters, No. 95, 2014: 15-23. Availability: <http://search.informit.com.au/documentSummary;dn=837394177454970;res=IELHSS> ISSN: 1030-2646.
Are data available to others outside study team? Yes, Australian and International researchers can apply for a low-cost licence to use LSAC data. LSAC; the Longitudinal Study of Australian Children is the parent study of the Child Health CheckPoint. LSAC Waves 1-5 are currently available to LSAC licence holders, and the Australian Institute of Australian Studies periodically releases additional LSAC data as available. The Child Health CheckPoint data will be released to LSAC licence holders in late 2017.
Study focus (e.g. social development) The Longitudinal Study of Australian Children (LSAC, www.growingupinaustralia.gov.au) is Australia’s largest and only nationally-representative children’s longitudinal study. The study commenced in 2004 with two cohorts (n≈10,000) – 0-1 year old infants (B cohort) and 4-5 year old children (K cohort). It is governed by the Department of Social Services, the Australian Institute of Family Studies (AIFS) and the Australian Bureau of Statistics (ABS). The cohorts are followed biannually, with a broad focus including health and development, education, family and parenting characteristics and socioeconomic environment. A new phase, LSAC’s Child Health CheckPoint is a one-off physical health and biospecimens module for the younger B cohort. It will travel around Australia in 2014-2015, collecting important information about children’s cardiovascular and respiratory health, fitness, strength, vision, hearing, diet, activity and more, as they transition from childhood to adolescence. The study children will be aged 11-12 years old and we expect 3000-4000 children to participate. The Child Health CheckPoint is conducted by researchers at the Murdoch Childrens Research Institute.
Sampling frame LSAC had a two-stage clustered sampling design, first randomly selecting 10% of all Australian postcodes (stratified by state and urban/rural), then selecting children within those postcodes registered in Medicare Australia’s database and aged either 3-19 months old (Baby cohort) or 4-5 years old (Kindergarten cohort).
CheckPoint: The Baby cohort
Year commenced LSAC: The first data collection wave was in 2004
CheckPoint: The data collection wave is in 2014-2015
Commencement sample (N) LSAC: Baby cohort n = 5107. Kindergarten cohort n = 4983
CheckPoint: 1875 (plus 1875 parents)
Annual attrition rate* (%) LSAC: Participation at Wave 5 (2012) was Baby cohort n = 4070. Kindergarten cohort n = 3930
CheckPoint: Not applicable
Intergenerational? LSAC: No, but parents complete questionnaires about themselves and child
CheckPoint: One of each child’s parents is also assessed
Imaging (FMRI, Ultrasound, etc)? LSAC: No
CheckPoint: Retinal photography, 2D photos of face, carotid intima-media thickness (cIMT), 3D photo of face and teeth, peripheral quantitative computerised tomography (pQCT) of cortical and trabecular bone density compartments
Linkage (BioGrid, VPDC, NAPLAN etc)? LSAC: Medicare Australia (including immunisation) database, National Childcare Accreditation Council data, ABS Census of Population and Housing data, National Assessment Program Literacy and Numeracy scores, My Schools data
CheckPoint: Perinatal Data Form (consent to link; linkage to follow)
Biosamples (e.g., buccal, blood): LSAC: None
CheckPoint: 30mL venous blood (plasma, serum, and proteomics tubes); if refused fingerprick. Saliva, urine, hair, toenail clippings, buccal swab and Newborn screening card
Other approvals or requirements PedsQL 4.0 Generic Core Scale (Child Report 8-12yrs)
PedsQL General Wellbeing Scale (Child Report 8-12yrs)
AQoL 8D
Child Health Utility 9D (CHU9D)
International Survey of Children’s Wellbeing (ISCWeB) 2013
Manchester Pain Manikin
Wave Year Age (mean, range) Eligible sample (not deceased, not withdrawn)
LSAC Wave 1 2004 Baby (B) cohort: 3-19 months
Kinder (K) cohort: 4-5 years
B: 5107
K: 4983
LSAC Wave 2 2006 B: 2-3 yrs
K: 6-7 yrs
B: 4606 (90%)
K: 4464 (90%)
LSAC Wave 3 2008 B: 4-5 yrs
K: 8-9 yrs
B: 4386 (86%)
K: 4331 (87%)
LSAC Wave 4 2010 B: 6-7 yrs
K: 10-11 yrs
B: 4241 (83%)
K: 4164 (84%)
LSAC Wave 5 2012 B: 8-9 yrs
K: 12-13 yrs
B: 4070 (80%)
K: 3930 (78.9%)
LSAC Wave 6 2014 B: 10-11 yrs
K: 14-15 yrs
B: 3764 (73.7%)
K: 3537 (71.0%)
LSAC’s Child Health CheckPoint 2015 B: 11-12 yrs B: 1875 (plus 1875 parents)
LSAC Wave 7 2016 B: 12-13 yrs
K: 18-19 yrs
To be determined
Future LSAC waves Study has ongoing funding, subject to future government decisions.

Principal Investigator

Professor Melissa Wake

Ph: +613934 55761
Email: melissa.wake@mcri.edu.au

Project Manager

Dr Susan Clifford

Ph: +613934 57620
Email: susan.clifford@mcri.edu.au

Postal Address

Child Health CheckPoint

Murdoch Childrens Research Institute
The Royal Children’s Hospital
Flemington Road
PARKVILLE VIC 3052
Ph: 1800 784 748
Email: LSAC.ChildHealthCheckPoint@mcri.edu.au