LifeCourse A Melbourne Children's Research Initiative

CAP and NICAP: Bioanalyses and omics

Relevant LifeCourse Constructs	Year	2011-2012	2013-2014	2014-2016	2014-2016	2016-2017	2016-2017	2018-2019	2018-2019
	Wave	1 (CAP)	2 (CAP)	3 (CAP)	3a (NICAP)	4 (CAP)	4a (NICAP)	5 (CAP)	5a (NICAP)
	Age	7 years	8.5 years	10 years	10 years	11.5 years	11.5 years	13 years	13 years
	N	Total: 497 Cases: 179 Controls: 212 High risk: 100	Total: 485 Cases: 206 Controls: 174 High risk: 83	Total: 481 Cases: 167 Controls: 192 High risk: 80	Total: 122 Cases: 59 Controls: 54 High risk: 6		Total: 122 Cases: 59 Controls: 54 High risk: 6		Total: 122 Cases: 59 Controls: 54 High risk: 6
Epigenotyping						O:EPIC ^I Substudy: 178		O:EPIC ^I Substudy: 40		O:EPIC ^I Substudy: 100
Genotyping						O:GSA-MD ^I Substudy: 214
Hormone measurement						O:DHEA-A ^I Substudy: 170 O:T-A ^I Substudy: 173 O:E-A ^I Substudy: 56		O:DHEA-A ^I Substudy: 146 O:T-A ^I Substudy: 165		O:DHEA-A ^I Substudy: 127 O:T-A ^I Substudy: 127

Featured measurements

DHEA-A: : Dehydroepiandrosterone (DHEA) analysis
E-A: : Estradiol analysis
GSA-MD: : Illumina Infinium Global Screening Array – Multi-Disease - Bioanalysis
EPIC: : Illumina Infinium MethylationEPIC BeadChip Array v1.0 - Bioanalysis
T-A: : Testosterone analysis

Legend

B: = Biosample collected
BA: = Biosample analysis
G: = Grandparent(s) completed questionnaire
L: = Data linkage
N: = Nurse completed questionnaire
O: = Observation or direct assessment
Of: = Offspring completed questionnaire
P: = Parent/guardian completed questionnaire
Pe: = Peer completed questionnaire
R: = Records abstraction
S: = Self (primary participant) completed questionnaire
T: = Teacher completed questionnaire
X: = Other source
X ^F: = Pertains to father
X ^Fam: = Pertains to family
X ^G: = Pertains to grandparent(s)
X ^I: = Pertains to primary participant
X ^IP: = Pertains to partner
X ^M: = Pertains to mother
X ^O: = Pertains to offspring
X ^P: = Pertains to parent/guardian(s)
X ^Pe: = Pertains to peers
X ^Si: = Pertains to sibling(s)
X ^T: = Pertains to teacher(s)
X ^X: = Pertains to other reportees

Metadata presented by LifeCourse provides a crucial first step in understanding the available data across studies. It does not take the place of detailed study documentation, which should always be consulted during design and analysis.