COBRA: Bioanalyses and omics
Relevant LifeCourse Constructs | Year | 2009-Ongoing | 2009-Ongoing |
---|---|---|---|
Phase | Baseline | Clinic Visit | |
Age | 2-18 years | 2-18 years | |
N | in progress | in progress | |
Epigenotyping | BA:CEpi I | ||
Gene expression assay | BA:COBRA I | ||
Genotyping | BA:CGen I | ||
Hormone measurement | BA:C-HM I 1 | ||
Metabolic function test | BA:C-MA I 2 | ||
Renal function | BA:COBRA I | ||
Vitamin D measurement | BA:COBRA I |
Featured measurements
- CEpi
-
: Candidate Epigenotyping Protocol - CGen
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: Candidate Genotyping Protocol - COBRA
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: Childhood Overweight BioRepository of Australia Study-devised measure - C-HM
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: COBRA Devised - Hormone Measurement Protocol - C-MA
-
: COBRA Devised - Metabolic Analyses measure
Notes
1
Hormone measurements on blood and urine samples included (for example) FSH, LH, PTH, testosterone, androgen, thyroid function, adiponectin, leptin, resistin. For further information, contact COBRA
2
Metabolic profile analyses on blood samples included liver function, lipid profile, insulin, glucose (fasting for < 10 year olds, oral glucose tolerance test for ≥ 10 year olds), vitamins and minerals. For further information, contact COBRA
Legend
- B
= Biosample collected- BA
= Biosample analysis- G
= Grandparent(s) completed questionnaire- L
= Data linkage- N
= Nurse completed questionnaire- O
= Observation or direct assessment- Of
= Offspring completed questionnaire- P
= Parent/guardian completed questionnaire- Pe
= Peer completed questionnaire- R
= Records abstraction- S
= Self (primary participant) completed questionnaire- T
= Teacher completed questionnaire- X
= Other source- X F
-
= Pertains to father - X Fam
-
= Pertains to family - X G
-
= Pertains to grandparent(s) - X I
-
= Pertains to primary participant - X IP
-
= Pertains to partner - X M
-
= Pertains to mother - X O
-
= Pertains to offspring - X P
-
= Pertains to parent/guardian(s) - X Pe
-
= Pertains to peers - X Si
-
= Pertains to sibling(s) - X T
-
= Pertains to teacher(s) - X X
-
= Pertains to other reportees
Metadata presented by LifeCourse provides a crucial first step in understanding the available data across studies. It does not take the place of detailed study documentation, which should always be consulted during design and analysis.