LifeCourse A Melbourne Children's Research Initiative

MIS BAIR: Health services

Relevant LifeCourse Constructs	Year	2013-2016	2013-2016	2013-2016	2013-2016	2013-2016	2014-2017	2014-2017	2014-2018	2018	2015-2018	2015-2018	2016-2019	2016-2019	2017-2020	2017-2020	2018-2021	2018-2021	2021	2020	2021	2022	2022	2022	2022	2022	2022
	Phase	Recruitment (pre-birth)	Randomisation/birth	Discharge from hospital	7 days post randomisation	3 months	6 months	9 months	12 months	End Part 1	18 months	24 months	30 months	36 months	42 months	48 months	54 months	60 months	End Part 2	COVID Immune: Baseline	COVID Immune: 12mth follow-up	COSI BAIR: Visit 1	COSI BAIR: Visit 1 +7 days	COSI BAIR: Visit 2	COSI BAIR: Visit 2 + 7 days	COSI BAIR: Visit 2 + 28 days	COSI BAIR: Visit 2 + 182 days
	Age	Pre-birth	Birth	Birth	Early infancy	3 months	6 months	9 months	12 months	End Part 1	18 months	24 months	30 months	36 months	42 months	48 months	54 months	60 months	End Part 2	5-6 years	End COVID Immune	5-11 years	5-11 years	5-11 years	5-11 years	5-11 years	End COSIBAIR
	N	1272 Total 637 BCG 635 no BCG	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Complete	Substudy: 50	Complete	Complete	Complete	Complete	Complete
Adverse event				P:MIS BAIR ^I O:MIS BAIR ^I	P:MIS BAIR ^I O:MIS BAIR ^I	P:MIS BAIR ^I O:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I		P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I				O:BNT162b2-VA ^I		O:BNT162b2-VA ^I
Dental examination																			O:MIS BAIR ^I ¹
Hospital admission							P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I		P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I	P:MIS BAIR ^I								N:COSI BAIR ^I	N:COSI BAIR ^I
Immunisation status			R:H-R ^M P:MIS BAIR ^M
Seen by service							P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I		P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I	P:MIS BAIR ^I P:ISAAC ^I		P:COVID-Im ^P ² P:COVID-Im ^I ²	P:COVID-Im ^P ² P:COVID-Im ^I ²
Vaccination given																							O:BNT162b2-VA ^I		O:BNT162b2-VA ^I

Featured measurements

BNT162b2-VA: : BNT162b2 COVID-19 vaccine administration protocol
COSI BAIR: : COVID-19 Specific vaccine and heterologous Immunity in the Melbourne infant study of BCG for Allergy and Infection Reduction devised measure
COVID-Im: : COVID-Immune Study-devised measure
H-R: : Hospital Records
ISAAC: : International Study of Asthma and Allergies in Children
MIS BAIR: : The Melbourne Infant Study: BCG for Allergy and Infection Reduction Study-devised measure

Notes

Optional assessment

Information collected fortnightly over a 12 month period

Legend

B: = Biosample collected
BA: = Biosample analysis
G: = Grandparent(s) completed questionnaire
L: = Data linkage
N: = Nurse completed questionnaire
O: = Observation or direct assessment
Of: = Offspring completed questionnaire
P: = Parent/guardian completed questionnaire
Pe: = Peer completed questionnaire
R: = Records abstraction
S: = Self (primary participant) completed questionnaire
T: = Teacher completed questionnaire
X: = Other source
X ^F: = Pertains to father
X ^Fam: = Pertains to family
X ^G: = Pertains to grandparent(s)
X ^I: = Pertains to primary participant
X ^IP: = Pertains to partner
X ^M: = Pertains to mother
X ^O: = Pertains to offspring
X ^P: = Pertains to parent/guardian(s)
X ^Pe: = Pertains to peers
X ^Si: = Pertains to sibling(s)
X ^T: = Pertains to teacher(s)
X ^X: = Pertains to other reportees

Metadata presented by LifeCourse provides a crucial first step in understanding the available data across studies. It does not take the place of detailed study documentation, which should always be consulted during design and analysis.