Trial phase Antenatal screening Antenatal Enrolment and Baseline Randomisation 6 w old follow-up 6 m old follow-up 1 y old follow-up 18 m old follow-up 2 y old follow-up End Phase 1 2.5 y old follow-up 3 y old follow-up 3.5 y old follow-up 4 y old follow-up 4.5 y old follow-up 5 y old follow-up 5.5 y old follow-up First year of school follow-up (5-6 y old) 6 y old follow-up *COVID-19 Supplement (6-7 y old) End Phase 2
Year 2013-2014 2013-2014 2013-2014 2013-2014 2013-2015 2014-2015 2014-2016 2015-2016 2015-2017 2016-2017 2016-2018 2017-2018 2017-2019 2018-2019 2018-2020 2019-2021 2019-2020 2020
Medical history P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC T:AvEDI 1 P:LSAC
General physical health S:SDV 2
Health services utilisation S:SDV P:SDV M C P:SDV M C P:PEI
P:PSQ
P:SDV M C
P:SDV M C P:PEI
P:PSQ
P:SDV M C
P:SDV M C P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
Hospitalisation(s) S:SDV P:SDV M C P:SDV M C P:SDV M C P:SDV M C P:SDV M C P:SDV M C P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
P:SDV M C
P:LSAC
Immunisations P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC
Injury(s) P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC P:LSAC
Health-related Quality of life S:AQOL-8D S:AQOL-8D S:AQOL-8D S:AQOL-8D
P:PedsQL-4.0
P:PedsQL-4.0 S:AQOL-8D
P:PedsQL-4.0
P:PedsQL-4.0 3 S:AQOL-8D
P:PedsQL-4.0
P:PedsQL-4.0 3 S:AQOL-8D
P:PedsQL-4.0
General physical functioning (e.g. getting
around, looking after yourself, household chores)
S:SDV 2 S:AQOL-8D S:AQOL-8D S:AQOL-8D S:AQOL-8D
P:PedsQL-4.0
P:PedsQL-4.0 S:AQOL-8D
P:PedsQL-4.0
P:PedsQL-4.0 3 S:AQOL-8D
P:PedsQL-4.0
P:PedsQL-4.0 3 S:AQOL-8D
P:PedsQL-4.0
Pain – general S:AQOL-8D S:AQOL-8D S:AQOL-8D S:AQOL-8D S:AQOL-8D S:AQOL-8D S:AQOL-8D
General health perception S:SRH S:SRH S:SRH P:SRH M C P:SRH M C P:SRH M C
P:LSAC 4
P:SRH M C
P:LSAC 4
P:SRH M C
P:LSAC 4
P:SRH M C
P:LSAC 4
P:SRH M C
P:LSAC 4
P:SRH M C
P:LSAC 4
P:SRH M C
P:LSAC 4
P:SRH M C
P:LSAC 4
P:SRH M C P:SRH M C
P:LSAC 4
Dental examination O:LTL O:LTL O:LTL
Tooth decay P:LSAC P:LSAC P:LSAC
Health literacy S:SDV 5 S:SDV 5 S:SDV 5 S:SDV 5
COVID-19 testing/infection P:CRISIS M C Fam 6
COVID-19 illness P:CRISIS M C Fam 6
Health behaviours S:ATPG3

Featured measurements

AQoL-8D: Assessment of Quality of Life - 8D
ATPG3: Australian Temperament Project Generation 3 derived
AvEDI: Australian version of the Early Development Instrument
CRISIS: CoRonavIruS Health Impact Survey (various instruments)
HOME: Home Observation for the Measurement of the Environment
LSAC: Longitudinal Study of Australian Children derived
LTL: Lift the Lip
PedsQL-4.0: Pediatric Quality of Life Inventory – 4.0 Generic Core Scales
PEI: Patient Enablement Index
PSQ: Patient Satisfaction Questionnaire
SDV: Study Devised Variable
SRH: Self-Rated Health

Notes

1 7 items from the AvEDI (as used in the 2018 Australian Early Development Census cycle) were used
2 Single item asking about whether any long-term illness, health problem or disability limits daily activities, including description of problem
3 Completed at half year assessment if not completed at previous assessment
4 2 items about concerns over child’s weight and perception of child’s weight
5 Self report items assessing mothers’ knowledge, attitudes and beliefs about paediatric health
6 Questions adapted from CRISIS Adult Self-Report and Parent / Caregiver, with adaptations shared with ATPG3

Legend

A = Administration report abstraction
C = Index child report (reporting on others)
L = Linkage (to other databases)
M = Medical records data abstraction
O = Observation/direct assessment
N = Nurse report
P = Parent/primary caregiver report
Pe = Peer report
S = Self report
T = Teacher report
X = Undefined
X BF = Pertaining to biological father
X BM = Pertaining to biological mother
C = Pertaining to index child
X F = Pertaining to father
X Fam = Pertaining to family
X G = Pertaining to grandparent(s)
X M = Pertaining to mother
X P = Pertaining to parent(s)
X Pa = Pertaining to partner
X Pe = Pertaining to peers
X Pr = Pertaining to primary caregiver
X Si = Pertaining to sibling(s)