Trial phase Antenatal screening Antenatal Enrolment and Baseline Randomisation 6 w old follow-up 6 m old follow-up 1 y old follow-up 18 m old follow-up 2 y old follow-up End Phase 1 2.5 y old follow-up 3 y old follow-up 3.5 y old follow-up 4 y old follow-up 4.5 y old follow-up 5 y old follow-up 5.5 y old follow-up First year of school follow-up (5-6 y old) 6 y old follow-up *COVID-19 Supplement (6-7 y old) End Phase 2
Year 2013-2014 2013-2014 2013-2014 2013-2014 2013-2015 2014-2015 2014-2016 2015-2016 2015-2017 2016-2017 2016-2018 2017-2018 2017-2019 2018-2019 2018-2020 2019-2021 2019-2020 2020
Speech P:ALSPAC 1 P:ALSPAC 1
Communication S:AQOL-8D O:HOME
S:AQOL-8D
O:HOME
S:AQOL-8D
P:CSBS-DP-ITC 2
S:AQOL-8D S:AQOL-8D S:AQOL-8D
P:SSIS 3
P:SSIS 3 4 T:SSIS 3 S:AQOL-8D
P:SSIS 3
Family history of
language and literacy problems
P:ELVS M F Si 5 P:ELVS BM BF Si P:ELVS BM BF Si P:ELVS BM BF Si P:ELVS BM BF Si
Language P:SDV 5
O:SDV 6
P:CSBS-DP-ITC 2
O:SDV 6
O:CELF-P2 7 O:SEAPART
O:CELF-P2 7
O:SEAPART
O:CELF-P2 7
T:LSAC 8
Reading T:LSAC 9 P:LSAC
Literacy O:SEAPART O:SEAPART T:LSAC 8

Featured measurements

ALSPAC: Avon Longitudinal Study of Parents and Children derived
AQoL-8D: Assessment of Quality of Life - 8D
CELF-P2: Clinical Evaluation of Language Fundamentals Preschool - Second Edition, Australian and New Zealand Standardised Edition
CSBS-DP-ITC: Communication and Symbolic Behavior Scales Developmental Profile Infant-Toddler Checklist
ELVS: Early Language in Victoria Study derived
HOME: Home Observation for the Measurement of the Environment
LSAC: Longitudinal Study of Australian Children derived
SDV: Study Devised Variable
SEAPART: School Entry Alphabetic and Phonological Awareness Readiness Test - Standardised Scoring
SSIS: Social Skills Improvement System

Notes

1 3 items measuring speech intellgibility were used
2 6 items from the CSBS-DP-ITC were used
3 The social skills composite only was used, which comprises of 7 subscales; communication, cooperation, assertion, responsibility, empathy, engagement, and self-control
4 Completed at half year phone interview if not completed at previous face-to-face visit
5 Study-devised 8-item language module, drawing from ELVS, CDI-WG and CSBS-DP-ITC
6 5 minute videos of unstructured play were analysed to measure maternal-child interactions (maternal responsive behaviours). Technique adapted from: Levickis, P., Reilly, S., Girolametto, L., Ukoumunne, O.C. and Wake, M. (2014). Maternal behaviors promoting language acquisition in slow-to-talk toddlers: prospective community-based study. J Dev Behav Pediatr, 35(4): 274-81. doi:10.1097/DBP.0000000000000056
7 The Sentence Structure, Word Structure, and Expressive Vocabulary subtests were used
8 A single global item was asked about language and literacy skills
9 5 items from the LSAC reading competencies scale were used

Legend

A = Administration report abstraction
C = Index child report (reporting on others)
L = Linkage (to other databases)
M = Medical records data abstraction
O = Observation/direct assessment
N = Nurse report
P = Parent/primary caregiver report
Pe = Peer report
S = Self report
T = Teacher report
X = Undefined
X BF = Pertaining to biological father
X BM = Pertaining to biological mother
C = Pertaining to index child
X F = Pertaining to father
X Fam = Pertaining to family
X G = Pertaining to grandparent(s)
X M = Pertaining to mother
X P = Pertaining to parent(s)
X Pa = Pertaining to partner
X Pe = Pertaining to peers
X Pr = Pertaining to primary caregiver
X Si = Pertaining to sibling(s)