The CATS study is a new and unique longitudinal study of children in metropolitan Melbourne as they approach adolescence. The study began in 2012 and will follow over 1200 children from grade 3 (8-9 years of age). The children will be visited once every year, and in 2013 completed the second wave of visits to participating students. The study will also collect information on parents and teachers.The main focus of the study is on the health and emotional development of children during the middle years of school with the aim of improving our understanding of the many influences that effect the health and emotional adjustment of children as they approach their teens. The study will look at the experiences of children and their families, their changing social context as they move into secondary school and their reactions to the biological changes of puberty.The information collected as part of this large study will help us identify when and how to promote the best health and emotional adjustment in pre-teens.



Study Summary
Study name Childhood to Adolescence Transition Study
Study abbreviation CATS
Current principal investigator/s Professor George Patton
Dr Lisa Mundy
Current project manager Dr Lisa Mundy
Primary Institution Murdoch Children’s Research Institute
Collaborating Institution/s University of Melbourne
University of South Australia
University of NSW
UCL Institute of Child Health, UK
La Trobe University, Australia
Deakin University, Geelong
University of Washington, Seattle USA
University of Birmingham, UK
University of Oregon, USA
Major funding sources National Health and Medical Research Council
Study website https://cats.mcri.edu.au/
Key reference for study (published study protocol) Mundy, L.K., Simmons, J.G., Allen, N.B., Viner, R.M., Bayer, J.K., Olds, T., Williams, J., Olsson, C., Romaniuk, H., Mensah, F., Sawyer, S.M., Degenhardt, L., Alati, R., Wake, M., Jacka, F. and Patton, G.C.. Study protocol: the Childhood to Adolescence Transition Study (CATS). BMC Pediatr. 2013 Oct 8;13:160. doi: 10.1186/1471-2431-13-160
Are data available to others outside study team? Yes, through study publication protocol coordinated by project manager.
Study focus (e.g. social development) The effect of puberty on health and emotional development.
Sampling frame All Grade 3 students (8-9 years of age) from a stratified cluster sample of schools in Melbourne, Australia were invited to take part.
Study type (e.g. randomised control trial, cohort, case-control) Longitudinal cohort
Year commenced 2012
Ongoing recruitment? Ongoing
Commencement sample (N) 1239
Intergenerational (e.g. offspring)? No
Imaging (e.g. fMRI, ultrasound, retinal photograph)? MRI, fMRI on iCATS nested study (n=128)
Linkage (e.g. BioGrid, VPDC, NAPLAN, Medicare)? NAPLAN (Victorian Curriculum and Assessment Authority)
Biosamples (e.g. buccal, blood, hair)? Saliva
Ethics approvals or requirements (e.g. specific, extended, unspecified, other)? This project only (Specific consent)
Future research related to this project (Extended consent)
Year Age (mean, range) Eligible sample (not deceased, not withdrawn)
2012 8.5 (8 – 11) years 1239 CATS
128 iCATS
2013 9.9 (8.8 – 11.5) years 1158 CATS
2014 10.9 (9.8 – 12.7) years 1119 CATS
2015 11 – 12 years 1066 CATS
TBD iCATS

Project Manager

Dr Lisa Mundy

Ph: +61 3 9345 7978
Email: lisa.mundy@mcri.edu.au