Year ≥ 2008
Time Enrolment
Age Pregnancy and birth Early life 0-3 years Childhood 3-12 years Teenage 13-19 years
Venous blood Cases: 537
Controls: 760
(as of October 2015, recruitment ongoing, ~60 per year)
Guthrie card from enrolment Cases: 537
Controls: 760
(as of October 2015, recruitment ongoing, ~60 per year)
Newborn screening (Guthrie) card consent at enrolment to link; linkage to follow
Synovial fluid (cases only) Cases: 82
(as of October 2015, recruitment ongoing, ~20 per year)
Saliva Cases and family members: 22 case families (81 samples total)
S – self report
P – parent report
C – child report
T – teacher report
N – welfare nurse
O – observation
XM: Mother
XF/P: Father/partner
XC: Child
XS: Sibling
XG: Grandparent