LifeCourse A Melbourne Children's Research Initiative

AQUA: Biosamples

Relevant LifeCourse Constructs	Year	2011-2012	2011-2012	2011-2012	2011-2012	2013-2014	2014-2015	2018-Ongoing
	Wave	1	2	3	4a	4	5	AQUA@6
	Age	19 weeks gestation	26 weeks gestation	36 weeks gestation	Birth	12 months	2 years	6-7 years
	N	2146	1715	1571	1401	1296	1038	In progress
Blood specimen from newborn						B:NBS ^I
Buccal			B:Buc ^M			B:Buc ^I			B:Buc ^I
Cord blood						B:Bl-Co ^I ¹
Placental tissue						B:Plac ^M ¹

Featured measurements

Bl-Co: : Blood, Cord sample
Buc: : Buccal sample
NBS: : Newborn Bloodspot Screening (Guthrie) card sample
Plac: : Placenta sample

Notes

A DNA biobank was created from samples of maternal and infant buccal cells, placental biopsies and cord blood mononuclear cells collected at birth, to allow for the examination of epigenetic states at birth as well as genetic factors in the mother and child

Legend

B: = Biosample collected
BA: = Biosample analysis
G: = Grandparent(s) completed questionnaire
L: = Data linkage
N: = Nurse completed questionnaire
O: = Observation or direct assessment
Of: = Offspring completed questionnaire
P: = Parent/guardian completed questionnaire
Pe: = Peer completed questionnaire
R: = Records abstraction
S: = Self (primary participant) completed questionnaire
T: = Teacher completed questionnaire
X: = Other source
X ^F: = Pertains to father
X ^Fam: = Pertains to family
X ^G: = Pertains to grandparent(s)
X ^I: = Pertains to primary participant
X ^IP: = Pertains to partner
X ^M: = Pertains to mother
X ^O: = Pertains to offspring
X ^P: = Pertains to parent/guardian(s)
X ^Pe: = Pertains to peers
X ^Si: = Pertains to sibling(s)
X ^T: = Pertains to teacher(s)
X ^X: = Pertains to other reportees

Metadata presented by LifeCourse provides a crucial first step in understanding the available data across studies. It does not take the place of detailed study documentation, which should always be consulted during design and analysis.