Generation Victorian (GenV)

Generation Victorian (GenV) aims to create large, parallel whole-of-state birth and parent cohorts for discovery and interventional research. GenV is open to all babies born in Victoria, Australia, and their parents over two years from mid-2021. Follow up blends study-collected, study-enhanced and linked data and biosamples. GenV is designed to address physical and mental health, and social issues experienced during pregnancy and childhood, as well as the antecedents of a wide range of diseases of ageing. It seeks to generate translatable evidence (prediction, prevention, treatments, services) to improve future wellbeing and reduce the future disease burden of children and adults.

Learn more about GenV at genv.org.au/for-researchers/

Study Summary
Study name Generation Victoria
Study abbreviation GenV
Current principal investigator/s Melissa Wake
Richard Saffery
Sharon Goldfeld
Ms Natasha Zaritski
Current project manager

Vanda Tedesco: Program Manager
Tony Frugier: Bio Discovery Stream Lead
William Siero: Cohort 2020s Stream Lead
Dr Yanhong Jessika Hu: Solutions Hub Co-Lead (Epidemiology)
Naomi Schwarz: Solutions Hub Co-Lead (Knowledge Translation and Engagement)
Kerri McAllen: Data Innovation Stream Lead

Primary Institution/s Murdoch Children’s Research Institute - MCRI
Collaborating Institution/s The Royal Children’s Hospital - RCH
The University of Melbourne, Department of Paediatrics - UoM
The Victorian Government - DHHS
Cross-sectoral coalition of partners – see https://genv.org.au/about-genv/supporters-and-partners/
Major funding source/s Paul Ramsay Foundation - PRF
Victorian State Government
Murdoch Children’s Research Institute - MCRI
The Royal Children’s Hospital Foundation - RCHF
Study website https://genv.org.au/ https://www.mcri.edu.au/genv
Study focus

GenV is conceptualised as very large birth and parent cohorts, open to all babies born in the state of Victoria over a two-year period and their parents. It will be multi-purpose, supporting observational, interventional, health services and policy research within the same cohort. It is designed to address physical and mental health and social issues experienced during childhood, as well as childhood and adult antecedents of health or disease during ageing. It seeks to generate translatable evidence (prediction, prevention, treatments, services) to improve future wellbeing and reduce the future disease burden of all children and adults.

Sampling frame

All Victorian newborns delivered over a 2-year period and their parents. Vanguard recruitment commenced at Joan Kirner Women & Children’s at Sunshine Hospital in December 2020. State-wide recruitment begins at other Victorian birthing services in mid-2021.

Primary study type Longitudinal cohort
Primary participant (at recruitment) Index child
Year commenced

2021

Is this study ongoing? Yes - the study is ongoing
Ongoing recruitment? Yes
Sample size (N)

Target: approximately 150,000 newborns and their parents

Survey data available? Yes
Imaging data available? No
Linkage to administrative dataset/s? Yes, linkage to (at least one) administrative dataset underway
Biosamples available? Yes
Are data available to others outside study team, with appropriate safeguards and structures in line with the cohort’s ethics and governance processes? Yes
Are there any costs associated with data/sample access for approved requests? There are usually no costs associated with access
Broadest type of participant consent available Unspecified consent (can be used for any future ethically approved research)
Study Contacts
Principal investigator/s Melissa Wake
Richard Saffery
Sharon Goldfeld
Ms Natasha Zaritski
Project manager

Vanda Tedesco: Program Manager
Tony Frugier: Bio Discovery Stream Lead
William Siero: Cohort 2020s Stream Lead
Dr Yanhong Jessika Hu: Solutions Hub Co-Lead (Epidemiology)
Naomi Schwarz: Solutions Hub Co-Lead (Knowledge Translation and Engagement)
Kerri McAllen: Data Innovation Stream Lead

Study Contact

Email: GenVHQ@mcri.edu.au
Address: Murdoch Children's Research Institute,
Royal Children’s Hospital
Flemington Road, Parkville
Victoria 3052 Australia