MIS BAIR: Allergies

Trial phase Recruitment Randomisation/birth Discharge 7 days post randomisation 3 months 6 months 9 months 12 months End Part 1 18 months 24 months 30 months 36 months 42 months 48 months 54 months 60 months End Part 2
Year data collected 2013-2016 2013-2016 2013-2016 2013-2016 2013-2016 2014-2017 2014-2017 2014-2018 2015-2018 2015-2018 2016-2019 2016-2019 2017-2020 2017-2020 2018-2021 2018-2021
Wheezing P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS		 P:ISAAC
P:BIS
Asthma P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2		 P:SDV 3 P:SDV 3 P:SDV 3 P:SDV 3 P:SDV 3 P:SDV 3 P:SDV 3 P:SDV 3
Eczema P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2		 P:POEM
P:SDV 3		 P:POEM
P:SDV 3		 P:POEM
P:SDV 3		 P:POEM
P:SDV 3
O:SCORAD		 P:POEM
P:SDV 3		 P:POEM
P:SDV 3
O:SCORAD		 P:POEM
P:SDV 3		 P:POEM
P:SDV3
O:SCORAD		 P:POEM
P:SDV 3		 P:POEM
P:SDV 3		 P:POEM
P:SDV 3		 P:POEM
P:SDV 3
O:SCORAD
Epipen/Anapen prescription/use P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2		 P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN
Family history of allergy P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2
Food allergies P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2		 P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN
Hay fever P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2
Impact of allergies P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2
Other allergy P:HN BM BF Si 1 2
P:BIS BM BF Si 1 2		 P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN P:HN
Skin prick test 4 O:SPT O:SPT
Oral food challenge 4 O:OFC O:OFC

Featured measurements

BIS: Barwon Infant Study derived
BTS/SIGN:  British Thoracic Society (BTS) and the Scottish Intercollegiate Guidelines Network (SIGN) British guideline on the management of asthma
HN: HealthNuts Study derived
ISAAC: International Study of Asthma and Allergy in Children adaptation
OFC: Oral Food Challenge (HealthNuts protocol)
POEM: Patient-Oriented Eczema Measure
SCORAD: SCORing Atopic Dermatitis
SDV: Study Devised Variable
SPT: Skin Prick Test (HealthNuts protocol)

Notes

1 Full or half siblings only, not step-siblings
2 Family medical history questions are derived from HealthNuts and the Barwon Infant Study (BIS), and are based in part on ISAAC questions and BTS/SIGN guidelines (October 2014 version)
3 Asthma/eczema questions derived from BIS, ISAAC and BTS/SIGN guidelines
4 SPT and OFC protocols based on BIS and HealthNuts protocols

= Pertaining to peers X Pr = Pertaining to primary caregiver X Si = Pertaining to sibling(s)

Featured measurements

BIS: Barwon Infant Study derived
BTS/SIGN: British Thoracic Society (BTS) and the Scottish Intercollegiate Guidelines Network (SIGN) British guideline on the management of asthma
HN: HealthNuts Study derived
ISAAC: International Study of Asthma and Allergy in Children adaptation
OFC: Oral Food Challenge (HealthNuts protocol)
POEM: Patient-Oriented Eczema Measure
SCORAD: SCORing Atopic Dermatitis
SPT: Skin Prick Test (HealthNuts protocol)

Legend

A = Administration report abstraction
C = Index child report (reporting on others)
L = Linkage (to other databases)
M = Medical records data abstraction
O = Observation/direct assessment
N = Nurse report
P = Parent/primary caregiver report
Pe = Peer report
S = Self report
T = Teacher report
X = Undefined
X BF = Pertaining to biological father
X BM = Pertaining to biological mother
X C = Pertaining to index child
X F = Pertaining to father
X Fam = Pertaining to family
X G = Pertaining to grandparent(s)
X M = Pertaining to mother
X P = Pertaining to parent(s)
X Pa = Pertaining to partner
X Pe = Pertaining to peers
X Pr = Pertaining to primary caregiver
X Si = Pertaining to sibling(s)