Trans20 is a longitudinal cohort study comprising 620 children and adolescents. The study, which commenced in 2017, is embedded in standard clinical care at the Royal Children’s Hospital Gender Service (RCHGS). Trans20 aims to evaluate clinical outcomes of trans and gender diverse children and adolescents. Data is collected from patient during their episode of care with the service (~ yearly) and also once discharged (~every 24 months). Data is collected across multiple domains, including gender identity, mental health, physical health, quality of life and family functioning. This rich dataset offers tremendous opportunities to address important questions in the field of transgender health.

Study Summary
Study name Trans20
Study abbreviation Trans20
Current principal investigator/s Ken Pang
Michelle Telfer
Michelle Tollit
Carmen Pace
Monsurul Hoq
Primary Institution/s The Royal Children’s Hospital - RCH
Murdoch Children’s Research Institute - MCRI
Major funding source/s The Royal Children’s Hospital Foundation - RCHF
National Health and Medical Research Council - NHMRC
Hugh Williamson Foundation
Key reference for study Tollit, M. A., Pace, C. C., Telfer, M., Hoq, M., Bryson, J., Fulkoski, N., ... & Pang, K. C. (2019). What are the health outcomes of trans and gender diverse young people in Australia? Study protocol for the Trans20 longitudinal cohort study. BMJ open, 9(11), e032151.
Study focus

The Trans20 study aims to prospectively document the natural history of gender diversity in trans and gender diverse children and adolescents from Victoria, Australia, and to investigate long-term outcomes (gender, mental health, physical health, schooling, family functioning, quality of life) for those receiving gender affirming interventions.


Sampling frame

Participants include patients (aged 3-17 years old) who attended the Royal Children's Hospital Gender Service in Melbourne, Australia, between February 2017 and February 2020.


Primary study type Longitudinal cohort
Year commenced



Is this study ongoing? Yes - the study is ongoing
Ongoing recruitment? No
Sample size (N)



Survey data available? Yes
Imaging data available? No
Linkage to administrative dataset/s? No, no consent to link to administrative dataset(s) obtained
Biosamples available? No
Are data available to others outside study team, with appropriate safeguards and structures in line with the cohort’s ethics and governance processes? Yes
Are there any costs associated with data/sample access for approved requests? There are usually no costs associated with access
Broadest type of participant consent available

Questionnaires are completed as part of routine clinical care at RCH Gender Service and are analysed under a clinical audit framework. Long-term follow-up of patients who leave the Gender Service require specific consent.


Study Contacts
Principal investigator/s Ken Pang
Michelle Telfer
Michelle Tollit
Carmen Pace
Monsurul Hoq
Study Contact

Address: Department of Adolescent Medicine, Gender Service
Royal Children’s Hospital
Flemington Road, Parkville
Victoria 3052 Australia