LifeCourse A Melbourne Children's Research Initiative

VITALITY: Allergies

Relevant LifeCourse Constructs	Year	2014-2022	2014-2023	2014-2023	2014-2023	2020	2014-2023	2014-2023	2021	2021-2023	2014-2023	2023-Ongoing	2023-Ongoing
	Phase	Baseline	Compliance Monitoring	6 month follow-up	Optional Clinic Visit	COVID Immune: Baseline	9 month follow-up	12 month follow-up	COVID Immune: 12 month follow-up	Short Allergy Questionnaire	12mth Clinical assessment	6 year follow up	6 year Clinic assessment
	Age	6-12 weeks	3-12 months	6 months	6 months	1-5 years	9 months	12 months	2-6 years	12-24 months	12-18 months	6-7 years	6-7 years
	N	2739										in progress	in progress
Allergic reaction			P:VIT ^I P:VIT ^M P:VIT ^F P:VIT ^Si		P:VIT ^I			P:VIT ^I	P:VIT ^I		P:VIT ^I ¹	N:VIT ^I		N:VIT ^I
Allergic reaction management			P:VIT ^I P:VIT ^M P:VIT ^F P:VIT ^Si		P:VIT ^I			P:VIT ^I	P:VIT ^I
Allergic rhinitis
Allergy testing			P:VIT ^M									O:SPT ^I O:OFC ^I ²		O:SPT ^I O:OFC ^I
Anaphylaxis													L:VAN ^I
Anaphylaxis management													L:VAN ^I
Asthma			P:VIT ^M P:VIT ^F P:VIT ^Si										P:VIT ^M P:VIT ^F P:VIT ^Si P:VIT ^I P:ISAAC - Asth ^I
Coughing			P:VIT ^I		P:VIT ^I			P:VIT ^I	P:VIT ^I			P:VIT ^I	P:VIT ^I
Dermatitis						O:SCORAD ^I						O:SCORAD ^I		O:SCORAD ^I
Eczema			P:VIT ^I P:VIT ^M P:VIT ^F P:VIT ^Si		P:VIT ^I	P:VIT ^I O:SCORAD ^I		P:VIT ^I	P:VIT ^I			P:VIT ^I O:SCORAD ^I	P:VIT ^I P:VIT ^M P:VIT ^F P:VIT ^Si P:ISAAC - Ecz ^I P:POEM ^I	O:SCORAD ^I
Exercise-induced asthma
Family history of allergy			P:VIT ^M P:VIT ^F P:VIT ^Si										P:VIT ^M P:VIT ^F P:VIT ^Si
Food allergy			P:VIT ^I P:VIT ^M P:VIT ^F P:VIT ^Si		P:VIT ^I			P:VIT ^I	P:VIT ^I		P:VIT ^I ¹	N:VIT ^I	P:VIT ^I P:VIT ^M P:VIT ^F P:VIT ^Si	N:VIT ^I
Hay fever			P:VIT ^M P:VIT ^F P:VIT ^Si										P:VIT ^M P:VIT ^F P:VIT ^Si P:VIT ^I P:ISAAC - Rhin ^I
Impact of allergy													P:POEM ^I
Topical skin treatments			P:VIT ^I		P:VIT ^I								P:VIT ^I
Wheezing			P:VIT ^I		P:VIT ^I			P:VIT ^I	P:VIT ^I			P:VIT ^I	P:VIT ^I

Featured measurements

ISAAC - Asth: : International Study of Asthma and Allergies in Children - Asthma
ISAAC - Ecz: : International Study of Asthma and Allergies in Children - Eczema
ISAAC - Rhin: : International Study of Asthma and Allergies in Children - Rhinitis
OFC: : Oral Food Challenge
POEM: : Patient-Oriented Eczema Measure
VIT: : Primary prevention of infant food allergy: VITALITY Trial-devised measure
SCORAD: : SCORing Atopic Dermatitis
SPT: : Skin Prick Test - HealthNuts protocol
VAN: : Victorian Anaphylaxis Notifications

Notes

Administered to participants who did not complete the 12 mth follow-up

Administered to participants who had a positive skin prick test

Legend

B: = Biosample collected
BA: = Biosample analysis
G: = Grandparent(s) completed questionnaire
L: = Data linkage
N: = Nurse completed questionnaire
O: = Observation or direct assessment
Of: = Offspring completed questionnaire
P: = Parent/guardian completed questionnaire
Pe: = Peer completed questionnaire
R: = Records abstraction
S: = Self (primary participant) completed questionnaire
T: = Teacher completed questionnaire
X: = Other source
X ^F: = Pertains to father
X ^Fam: = Pertains to family
X ^G: = Pertains to grandparent(s)
X ^I: = Pertains to primary participant
X ^IP: = Pertains to partner
X ^M: = Pertains to mother
X ^O: = Pertains to offspring
X ^P: = Pertains to parent/guardian(s)
X ^Pe: = Pertains to peers
X ^Si: = Pertains to sibling(s)
X ^T: = Pertains to teacher(s)
X ^X: = Pertains to other reportees

Metadata presented by LifeCourse provides a crucial first step in understanding the available data across studies. It does not take the place of detailed study documentation, which should always be consulted during design and analysis.