The Triple B Pregnancy Cohort Study (Triple B)

The Triple B Pregnancy Cohort is a longitudinal study that examines a wide range of biopsychosocial factors that relate to the health and development of Australian children and families. Importantly, the project has a key focus on examining the impacts of alcohol, tobacco and other drug use in pregnant women and their partners during the prenatal period on infant development and family functioning. The results of this study will inform public health and treatment initiatives that improve the health and well-being of Australian children and families.

Study Summary
Study name The Triple B Pregnancy Cohort Study
Study abbreviation Triple B
Current principal investigator/s Delyse Hutchinson
Richard Mattick
Professor Craig Olsson (Royal Children’s Hospital)
George Youssef
Steve Allsop
Jacob Najman
Lucinda Burns
Elizabeth Elliott
Susan Jacobs
Samantha Teague
Current project manager

Tanja Capic

Primary Institution/s Deakin University
Collaborating Institution/s University of New South Wales
Curtin University
Murdoch Children’s Research Institute - MCRI
University of Sydney
University of Queensland
Major funding source/s National Health and Medical Research Council - NHMRC
Australian Rotary Health Mental Health of Young Australians Research Grant
Study website https://ndarc.med.unsw.edu.au/project/triple-b-bumps-babies-and-beyond
Key reference for study Hutchinson, D., Wilson, J., Allsop, S., Elliott, E., Najman, J., Burns, L., Bartu, A., Jacobs, S., Honan, I., McCormack, C., Rossen, L., Fiedler, H., Stone, C., Khor, S., Ryan, J., Youssef, G., Olsson, C.A. and Mattick, R.P. (2018). Cohort Profile: The Triple B Pregnancy Cohort Study: A longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and well-being of Australian children and families. International Journal of Epidemiology, 47(1): 26-27m. doi: 10.1093/ije/dyx126
Study focus

The Triple B Pregnancy Cohort Study investigates the effects of parental substance use and mental health on child development and family functioning. The data collected include demographic, parental, familial and infant factors, with a focus on parental substance use, mental health, parenting practices, familial functioning and child development.

Sampling frame

Women attending antenatal services attached to major hospitals, and specialist drug and alcohol antenatal services, in New South Wales and Western Australia (Australia).

Primary study type Longitudinal cohort
Year commenced

2009

Is this study ongoing? Yes - the study is ongoing
Ongoing recruitment? No
Sample size (N)

1623 families, 1534 mothers recruited through general antenatal clinics and 89 mothers recruited through specialist drug and alcohol antenatal clinics

Survey data available? Yes
Imaging data available? No
Linkage to administrative dataset/s? Yes, linkage to (at least one) administrative dataset underway
Biosamples available? Yes
Are data available to others outside study team, with appropriate safeguards and structures in line with the cohort’s ethics and governance processes? Yes
Are there any costs associated with data/sample access for approved requests? There are usually no costs associated with access
Broadest type of participant consent available Extended consent (can be used for future ethically approved research related to this project)
Wave Year Age Sample size (N)
1 2009-2013 Trimester 1 N(Total)=1621
2 2009-2013 Trimester 2 N(Total)=1596
3 2009-2013 Trimester 3 N(Total)=1579
4 2009-2013 Birth N(Total)=1479
5 2009-2013 8 weeks postnatal N(Total)=1460
6 2010-2014 Infancy N(Total)=1377
7 2013-2014 Preschool N(Substudy)=132
8 2017-Ongoing Middle childhood IN PROGRESS
Study Contacts
Principal investigator/s Delyse Hutchinson
Richard Mattick
Professor Craig Olsson (Royal Children’s Hospital)
George Youssef
Steve Allsop
Jacob Najman
Lucinda Burns
Elizabeth Elliott
Susan Jacobs
Samantha Teague
Project manager

Tanja Capic

Study Contact

Email: delyse.hutchinson@deakin.edu.au