Barwon Infant Study (BIS)
The Barwon Infant Study (BIS) is a pre-birth population derived cohort with over 1000 pregnant women recruited between 2010 and 2013. This study was designed to follow children born to the recruited mothers and observe them as they grow. BIS is an investigation into the early life origins of a range of non-communicable diseases in the modern environment.
BIS is being conducted as a partnership between Barwon Health, Deakin University and the Murdoch Children’s Research Institute. BIS is primarily funded by the National Health and Medical Research Council (NHMRC).
Study Summary | |
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Study name | Barwon Infant Study |
Study abbreviation | BIS |
Current principal investigator/s |
Peter Vuillermin Anne-Louise Ponsonby |
Current project manager |
Nakita Clements |
Primary Institution/s |
Murdoch Children’s Research Institute - MCRI
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Collaborating Institution/s |
Barwon Health
Deakin University |
Major funding source/s |
National Health and Medical Research Council - NHMRC
The Shane O’Brien Memorial Asthma Foundation Our Women’s Our Children’s fundraising committee The Cotton On Foundation The Jack Brockhoff Foundation |
Study website | https://www.barwoninfantstudy.org.au/ |
Key reference for study | Vuillermin, P., Saffery, R., Allen, K., Carlin, J., Tang, M., Ranganathan, S., Burgner, D., Dwyer, T., Collier, F., Jachno, K., Sly, P., Symeonides, C., McCloskey, K., Molloy, J., Forrester, M. and Ponsonby, A-L. (2015). Cohort Profile: The Barwon Infant Study. Int J Epidemiol, 44(4): 1148-60. DOI:10.1093/ije/dyv026 |
Study focus |
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Sampling frame |
Antenatal recruitment of eligible women from the Barwon region of Victoria (≤ 28 weeks gestation) |
Primary study type | Longitudinal cohort |
Primary participant (at recruitment) | Index child |
Year commenced |
2010 |
Is this study ongoing? | Yes - the study is ongoing |
Ongoing recruitment? | No |
Sample size (N) |
Recruitment commenced June 2010 to June 2013. A total of 1158 mothers were enrolled, with 1074 eligible infants making up the inception birth cohort |
Survey data available? | Yes |
Imaging data available? | Yes |
Linkage to administrative dataset/s? | Yes, linkage to (at least one) administrative dataset completed |
Biosamples available? | Yes |
Are data available to others outside study team, with appropriate safeguards and structures in line with the cohort’s ethics and governance processes? | Yes |
Are there any costs associated with data/sample access for approved requests? | There are usually no costs associated with access |
Broadest type of participant consent available |
Unspecified consent (can be used for any future ethically approved research) |
2020
O'Connor M, Ponsonby A-L, Collier F, Liu R, Sly PD, Azzopardi P, Lycett K, Goldfeld S, Arnup SJ, Burgner D, Priest N, Group TBI, Vuillermin P, Tang MLK, Saffery R, Carlin J, Harrison L. (2020). Exposure to adversity and inflammatory outcomes in mid and late childhood Brain Behavior & Immunity - Health, 9, 100146. DOI: 10.1016/j.bbih.2020.100146
Study Contacts | |
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Principal investigator/s |
Peter Vuillermin Anne-Louise Ponsonby |
Project manager |
Nakita Clements |
Study Contact |
Ph: +61 4 0043 2976 |