LifeCourse A Melbourne Children's Research Initiative

Domains

Domain	Constructs
Allergies	Allergic reaction management Allergic rhinitis Allergic skin rash Allergy testing Allergy to substance Anaphylaxis management Animal allergy Asthma Coughing Dermatitis Drug allergy Dry skin Eczema Exercise-induced asthma Exposure to peanut allergen Family history of allergy Food allergy Hay fever History of allergic reaction Impact of allergies Insect venom allergy Itchy skin Latex allergy Metal allergy Skin rash Topical skin treatments Wheezing
Anthropometrics	Abdominal circumference Abdominal skin fold thickness Anogenital distance Biceps skin fold thickness Birth abdominal circumference Birth head circumference Birth length Birth weight BMI - Body mass index Body composition Head circumference Height Hip circumference Image analysis Infant length Mid upper arm circumference Morphometric analysis Poor weight gain Pregnancy weight change Scapular skin fold thickness Skin-fold thickness Thigh circumference Triceps skin fold thickness Waist circumference Weight
Bioanalyses and omics	Adiponectin Alkaline phosphatase Allergen specific IgA antibody(s) Allergen specific IgE antibody(s) Allergen specific IgG antibody(s) Allergen specific IgM antibody(s) Alpha-1-acid glycoprotein Androgen Antibody measurement Biomarker analysis Biopsy report Blood calcium Blood glucose Cholesterol DBP - Vitamin D binding protein Diagnostic studies report Epigenotyping Expression analysis Faecal analysis Follicle stimulating hormone Free fatty acids Genotyping Growth hormone Haematology report High sensitivity C-reactive protein Hormone measurement Immune cell phenotyping Immunological measurement Immunology report Insulin Leptin Lipids Liver function Luteinising hormone Metabolic profile Metagenomics Microbiome analysis Minerals Oestrogen One-carbon metabolites Parathyroid hormone Prolactin Protein measurement Renal function Resistin Rheumatology report Sample assessed for infection Sample assessed for inflammation Sequencing Telomere length Testosterone Thyroid function Triglycerides Urine albumin Urine albumin/creatinine ratio Urine creatinine Vitamin D measurement Vitamins
Biosamples	Ascites Blood specimen from newborn Body fluid Bone marrow Breast milk Bronchial brushings Bronchoalveolar lavage fluid Buccal Capillary blood Cell line Central nervous system tissue Cerebrospinal fluid Colostrum Cord blood Dental plaque Dried blood spot Faeces Hair Induced Pluripotent Stem Cells Induced sputum Joint fluid Laboratory report Meconium Nail Nasal swab Oropharyngeal swab Pericardial fluid Placental tissue Saliva Skin swab Specimen processing Synovial fluid Tissue Tumour tissue Umbilical cord Urine Venous blood Whole tooth
Cardiovascular health	BP - Blood pressure Cardiac arrhythmia Cardiac function Cardiac interventions Cardiac transplant Cardiorespiratory fitness Clinical examination Family history of cardiovascular disease Haemodynamic measurements Heart rate History of cardiovascular disease History of cardioversion Intima media thickness Pacemaker Prior cardiac procedure(s) Retinal microvascular Thromboembolism Valvular regurgitation Ventricular function
Community environment	Access to transport Community involvement Community services Local facilities and amenities Neighbourhood safety Social capital Social participation Social support
Demographics	Aboriginal/Torres Strait Islander status Benefits and pensions Biological sex Country of birth Country of origin Current education Date of birth Employment status Ethnic group Financial circumstances Gender identity Household composition Housing ownership and tenure Income Language spoken Level of educational attainment Marital or partnership status Migrant status Moving to new residence Number of changes of school Number of dependant children Number of offspring Number of siblings Occupation Place in order of siblings Private health insurance Religious affiliation Residential locality Respondent information Sexual orientation Socioeconomic status
Education and childcare	Access to technology Assessment of needs Child care Current education Educational achievement Educational assistance In higher education Institutional policies Level of educational attainment Literacy Playgroup Pre-school Reading School attendance School engagement School environment School functioning School teacher Social participation Student-teacher relations Truancy Writing
Environmental exposures	Alcohol consumption during pregnancy Animal exposure Behaviour to prevent sun exposure Behaviour to prevent sun exposure during pregnancy e-cigarette user Environmental exposure Environmental exposures during pregnancy Exposure to pollution House dust Illicit drug use during pregnancy Personal hygiene Pet exposure Prenatal health behaviour Smoker in home Sun exposure Sun exposure during pregnancy Sunburn Tobacco use during pregnancy
Family environment	Aspirations Attachment behaviour Capacity for emotion Caregiver Characteristics of home environment Child protection service involvement Domestic abuse Domestic partner Family functioning Family relations Home learning environment Household chaos Intimate partner abuse Life events Number of dependant children Number of offspring Number of siblings Parental self-efficacy Parent-child relations Parenting behaviour Relationship satisfaction Sibling relations Social support
Health services	Access to healthcare services Access to services Adverse or serious adverse event(s) Age at admission Age at assessment Cardiac transplant Child development checks Clinical examination Cochlear implant service Cystic fibrosis screening Dental examination Early childhood intervention service Fontan procedure Health care costs Health literacy Hospital admission Immunisation status Maternal, child and family health service Medical assessment Medical examinations/reports Medical procedure or service Neonatal intensive care service Private health insurance Prophylactic antibiotic therapy Quality of health care Reason for action Respiratory therapy use Seen by audiology service Seen by cardiology service Seen by clinical immunology service Seen by dental surgery service Seen by dermatology service Seen by ear, nose and throat service Seen by endocrinology service Seen by gastroenterology service Seen by gastrointestinal surgery service Seen by general practitioner Seen by genetics service Seen by health professional Seen by hematology service Seen by nephrology service Seen by neurology service Seen by neurosurgery service Seen by occupational therapy service Seen by ophthalmology service Seen by orthopedic service Seen by physiotherapy service Seen by psychologist Seen by respiratory medicine service Seen by rheumatology service Seen by service Seen by speech and language therapy service Seen by surgeon Seen by urology service Seen in fertility clinic Seen in weight management clinic Treatment history
Hearing	Cause of hearing loss Ear infection Family history of hearing loss Grommet Hearing aid Hearing problem Hearing test
Imaging	Computerised tomography Echocardiogram Functional magnetic resonance imaging Image analysis Imaging report Intima media thickness Magnetic resonance imaging Morphometric analysis Photograph Ultrasound imaging
Medications and supplements	Antibiotics Antidepressants Change of medication Compliance behaviour to treatment Concomitant medications History of medication use History of supplement use Immunological therapy Medications Probiotics Supplements Topical skin treatments Vitamin D supplement therapy
Mental health and behaviour problems	Abusive behaviour Adjustment disorder Aggressive behaviour Altered thought processes Antisocial behaviour Anxiety Attachment behaviour Conduct disorder Criminal behaviour Cruel behaviour Defiant behaviour Delinquent behaviour Depression Dissociative disorder Disturbance of attention Eating disorder Emotional adjustment Emotional problems Excessive crying of infant Family history of mental disorder Fear of injury Fussy infant Hostile behaviour Hyperactive behaviour Involved in legal proceedings Involved with police Loneliness Mania Obsessive compulsive behaviour Panic attack Personality disorder Pervasive developmental disorder Phobia Postpartum depression Posttraumatic stress disorder Problem behaviour Psychiatric diagnosis Psychomotor agitation Psychosis Psychosocial functioning Schizophrenia Seen by psychologist Self-harm Separation anxiety Social behaviour Social phobia Somatic syndrome Stress Suicidal thoughts Temper tantrums Tics Violent behaviour
Methodology	Acceptability of intervention Clinical trial group Compliance behaviour to treatment Consent for participation Eligibility for trial Honesty in survey response Incidental unblinding Intervention given Non-respondent information Participation status in research Placebo given Pre-assessment health check Randomisation Researcher Respondent information Treatment given Treatment group Withdrawal from trial
Miscellaneous	Ability to drive Gambling Has access to weapon Managing personal finances Parental consanguinity Perceived body shape Religiousness Sucking behaviour Toilet trained
Neurocognitive development	Ability to imitate Arithmetic reasoning Assessment of needs Attention Child development status Cognitive functions Communicates with gestures Communication skills Developmental screening Executive cognitive functions Family history of learning disability Intellectual disability Intelligence Language development Learning disability Memory Memory assessment Motor function Neurodevelopmental disorder Persistence Pervasive developmental disorder Play behaviour Processing capacity Processing speed Social-emotional development Tics Visuospatial reasoning
Nutrition	Attitude towards diet Caffeine intake Dietary intake Dietary supplements Eating behaviour and appetite Eating problem Feeding problem Health literacy Infant feeding
Other health information	Activity of daily living Age at diagnosis Age at onset Birthmark Bladder management Bleeding Bone density Bowel incontinence Bowel management Burden of Illness Cause of illness or injury Communication about health Comorbid conditions Congenital disorder COVID-19 infection COVID-19 testing Date of diagnosis Death Diabetes mellitus Diagnostic studies report Disease management Disease presentation Disease progression Disease severity Dysmorphism Economic impact of disorder Exposure to viral disease Eye infection Family history of cystic fibrosis Family history of diabetes mellitus Family history of disorder Family history of obesity Family history of stroke Family medical history Fatigue Food intolerance Frequency of bowel action Gastroesophageal reflux disease Gastrointestinal symptom General wellbeing Health perceptions Health promoting behaviour Heartburn Illness Irritable bowel Medical diagnosis Medical examinations/reports Medical history Migraine Mobility Nausea Neonatal seizures Neural tube defect Oral health Osteoporosis Osteoporotic fracture Pain Pathology report Pelvic floor dysfunction Physical health problems Postmortem examination done Post-operative complications Prognosis/outlook Protein-losing enteropathy Response to immunisation Response to treatment Sensory function Serious childhood illness or injury Signs and symptoms Skin Stomach ache Swallowing problem Tooth decay Type of diagnosis Understanding of condition Urinary incontinence Viral infection Visual acuity Vital signs Vitamin D deficiency Wounds and Injuries
Peer relationships	Bullying Peer relationship Victim of bullying
Physical activity	Cardiopulmonary fitness test Domestic activity Leisure activities Muscle function test Physical activity Physical activity assessment Sedentary lifestyle Sports activity
Physical appearance	Birthmark Constitutive skin colour Freckles Hair colour Iris (eye) colour Skin type
Pregnancy and birth	Admission to neonatal intensive care unit Admission to special care baby unit Adoption Amnionicity determination in multiple birth Apgar score Attitudes towards pregnancy Behaviour to prevent sun exposure during pregnancy Biological parents' age at time of delivery Birth abdominal circumference Birth head circumference Birth hospital demographics Birth length Birth weight Birth weight abnormality Chorionicity determination in multiple birth Communication about in-vitro fertilisation Complications during labour and delivery Complications during pregnancy Complications during puerperium Conception method Congenital disorder Contraception Decreased oestriol level Due date Fetal disorder Fetus and neonate conditions Gestational age at birth Gestational diabetes Gestational hypertension History of ectopic pregnancy History of miscarriage History of stillbirth Immunisation at birth Induced abortion Infectious disease complicating childbirth Labour established Last menstrual period Length of hospital stay Location of birth Maternal risk factors Maternity leave Mid upper arm circumference Multiple birth Multiple birth order Multiple pregnancy Neonatal assessments Neonatal intensive care service Obstetric history Parity Patient transfer to skilled nursing facility Pattern of delivery Place of birth Placental details Postpartum health behaviour Pre-eclampsia Pregnancy weight change Prenatal health behaviour Presentation of fetus Resuscitation of neonate Season of birth Steroid hormone Teenage pregnancy Thigh circumference Time of delivery Time to pregnancy Time to spontaneous respirations Twin placenta examination Zygosity determination in multiple birth
Psychosocial wellbeing	Body image Caregiver Connection to nature Coping behaviour Emotional adjustment Emotional wellbeing Interpersonal relations Level of optimism Life events Loneliness Mental flexibility Mindfulness Prosocial behaviour Psychological resilience Psychosocial functioning Quality of Life Quality of life satisfaction Racial discrimination Self efficacy Self-care behaviour Self-esteem Sense of identity Social skills Social values Values Victim of crime Work-life balance
Puberty	Acne Age at menarche Bone age Menstruation Puberty stage
Respiratory health	Allergic rhinitis Asthma Bronchial brushings Bronchoalveolar lavage Bronchoalveolar lavage fluid Chest examination Coughing CT of chest Difficulty breathing Electrical impedance tomography Exercise-induced asthma Hay fever Induced sputum Lower respiratory tract infection Lung function tests Plastic bronchitis Respiratory disorder Respiratory therapy use Respiratory tract infection Sputum Wheezing
Romantic relationships	Intimate partner abuse Intimate partner relations Relationship satisfaction
Screen and technology use	Access to technology Screen time Social media Video games
Sexual health and activity	History of sexually transmitted infection Sexual activity Sexual health Sexual relations
Sleep	Quality of sleep Settling method Sleep behaviour Sleep disorder Sleep problem Sleep studies
Speech and language	Communication skills Comprehension Family history of speech and language disorder Language Language development Seen by speech and language therapy service Social skills Speech Stuttering Vocabulary Voice
Substance use	Alcohol consumption Alcohol consumption during pregnancy Alcohol drinking behaviour Caffeine user Driving under the influence Drug injection behaviour Drug misuse behaviour Drug seeking behaviour e-cigarette user Family history of substance abuse Illicit drug use during pregnancy Illicit substance use Institutional policies Marijuana user Smoker Substance abuse prevention education Tobacco smoking behaviour Tobacco use Tobacco use during pregnancy
Temperament and personality	Curiosity Fussy infant Impulse self-control Persistence Personality Sensation seeking Temperament